MRONJ: Pathophysiology, Non-Surgical and Surgical Management

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Medication-related osteonecrosis of the jaw (MRONJ) has emerged as a challenging clinical problem since its initial description in 2003. As understanding of MRONJ has increased, so too has the incidence owing to longer life expectancies and the development of novel therapeutics that adversely impact bone metabolism. OMSs must thus be well-versed in all aspects of management of this disease. This course will provide a comprehensive summary of MRONJ that can equip attendees with the knowledge and tools to confidently manage all stages of MRONJ. Discussions will review the pathophysiology, strategies for both surgical and non-surgical management and appraisal of the current literature and emerging treatments. Case presentations will showcase successful outcomes and pitfalls learned from challenging cases.

Learning Objectives

At the conclusion of this program, participants should be able to:

  1. Discuss the pathophysiology and disease mechanisms of MRONJ.
  2. Describe how to counsel patients regarding surgical and non-surgical management of MRONJ.
  3. Analyze the current literature regarding expected outcomes and emerging treatments.


Joshua Lubek, DDS, MD
Professor
University of Maryland
Baltimore, Maryland
Disclosure(s): No financial relationships to disclose

Cameron Lee, DMD, MD
Assistant Professor
University of Maryland Medical Center
Baltimore, Maryland
Disclosure(s): No financial relationships to disclose

An Internet-based CDE/CME Activity
Original Release Date: September 9, 2024
Expiration Date: September 9, 2027
Estimated time to complete this educational activity: 0.50 hour
Method of participation: Self-Study

Joshua Lubek, DDS, MD

Professor

University of Maryland

Dr. Joshua Lubek was born in Toronto, Ontario, Canada. He received his medical degree from Wayne State University School of Medicine, Detroit, Michigan and his dental degree from the University of Western Ontario, London, Ontario, Canada. He completed both a General Surgery internship and an Oral and Maxillofacial Surgery residency program at Henry Ford Hospital in Detroit, Michigan.

Dr. Lubek subsequently completed a 2-year Head and Neck Surgery/Microvascular Reconstructive Surgery fellowship at the University of Maryland Greenebaum Cancer Center, Baltimore, Maryland.

Dr. Lubek is currently a Professor and fellowship director of the Oral-Head & Neck Oncology/Microvascular Surgery program in the Department of Oral & Maxillofacial Surgery at the University of Maryland. He is actively involved in the training of surgical fellows, residents, dental students and medical students. Dr. Lubek is involved with research in the areas of Head and Neck Cancer as well as Microvascular Surgery and continues to publish and lecture (nationally and internationally) on these subjects. Dr. Lubek also serves as the director for Oral & Maxillofacial Hospital Services at the University of Maryland Medical Center.

Dr. Lubek’s clinical interests are focused on Head and Neck Surgery (malignant and benign tumors including salivary gland and thyroid pathology), Microvascular Reconstructive Surgery, Transoral Robotic Surgery (TORS) and Maxillofacial Trauma Surgery.

Disclosure(s): No financial relationships to disclose

Cameron Lee, DMD, MD

Assistant Professor

University of Maryland Medical Center

Dr. Cameron Lee is originally from Honolulu, Hawaii. He received his dental degree from Harvard School of Dental Medicine, medical degree from Harvard Medical School, and completed surgical residency at Massachusetts General Hospital. Following residency he pursued fellowship training in Head and Neck Oncology and Microvascular Surgery at the University of Maryland. He is currently Assistant Professor and Associate Program Director in the University of Maryland Department of Oral and Maxillofacial Surgery.

Disclosure(s): No financial relationships to disclose

Continuing Education Provider Approval
The American Association of Oral and Maxillofacial Surgeons is an ADA CERP Recognized Provider.

ADA CERP is a service of the American Dental Association to assist dental professionals in identifying quality providers of continuing dental education.

ADA CERP does not approve or endorse individual courses or instructors, nor does it imply acceptance of credit hours by boards of dentistry.

The American Association of Oral and Maxillofacial Surgeons designates this activity for 0.5 continuing education credit(s).

AGD - Accepted Program Provider
FAGD/MAGD Credit
11/1/22-12/31/26
Provider ID# 214680

The American Association of Oral and Maxillofacial Surgeons (AAOMS) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The American Association of Oral and Maxillofacial Surgeons designates this internet-based enduring material for a maximum of 0.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Key:

Complete
Failed
Available
Locked
Faculty and Planner Disclosure
Pre-Quiz
5 Questions  |  1 attempt  |  0/5 points to pass
5 Questions  |  1 attempt  |  0/5 points to pass
MRONJ: Pathophysiology, Non-Surgical and Surgical Management
Open to view video.  |  30 minutes
Open to view video.  |  30 minutes
Post-Quiz
5 Questions  |  Unlimited attempts  |  4/5 points to pass
5 Questions  |  Unlimited attempts  |  4/5 points to pass
Evaluation
11 Questions
Certificate
0.50 CDE/CME credits  |  Certificate available
0.50 CDE/CME credits  |  Certificate available